Nous aurons le plaisir d'accueillir Jessica Bolker,Associate Professor, University NewHampshire.
Titre : Using models: from biology to philosophy, and back
Résumé : The first part of this talk focuses on philosophy of biology: specifically, epistemological issues related to the use of model organisms in biological research. These issues include the importance of biological and epistemological contexts, and matters of similarity, representation, and inference. The second part examines the implications of these epistemological concerns in the realm of translational science (that is, translating basic biological research findings into biomedical applications), which relies heavily on animal models as proxies for humans. Translational science faces many challenges; I argue that some of them may arise from the way animal models are used. A philosophical perspective on models can help to identify epistemological obstacles to translation, and contribute to overcoming them. This approach exemplifies Bill Wimsatt’s “philosophy for biology”, and may help bridge the disciplinary gap between philosophy and science, as well as the
translational gap between mice and men.